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Another indole reported in the mid-90s 7-hydroxymitragynine C23H30N2O5 is present in much lesser amounts 2% of total alkaloids but with the most potent opioid agonist and analgesic effect. On animal studies the analgesic activity is reported to be 10x – 17x that of morphine. Other potency comparisons with morphine is from 6x orally with better oral absorption and 2x
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